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Mislocated FUS is sufficient for gain-of-toxic-function amyotrophic lateral sclerosis phenotypes in mice.
Published in:
2016
By:
- Gen Shiihashi;
- Daisuke Ito;
- Takuya Yagi;
- Yoshihiro Nihei;
- Taeko Ebine;
- Norihiro Suzuki;
- Shiihashi, Gen;
- Ito, Daisuke;
- Yagi, Takuya;
- Nihei, Yoshihiro;
- Ebine, Taeko;
- Suzuki, Norihiro
Publication type:
journal article
Dominant ER Stress-Inducing Mutations Underlie a Genetic Syndrome of Neonatal/Infancy-Onset Diabetes, Congenital Sensorineural Deafness, and Congenital Cataracts.
Published in:
2017
By:
- De Franco, Elisa;
- Flanagan, Sarah E.;
- Takuya Yagi;
- Abreu, Damien;
- Mahadevan, Jana;
- Johnson, Matthew B.;
- Jones, Garan;
- Acosta, Fernanda;
- Mulaudzi, Mphele;
- Ngee Lek;
- Oh, Vera;
- Petz, Oliver;
- Caswell, Richard;
- Ellard, Sian;
- Fumihiko Urano;
- Hattersley, Andrew T.;
- Yagi, Takuya;
- Lek, Ngee;
- Urano, Fumihiko
Publication type:
journal article
Metronidazole-induced encephalopathy and myoclonus: Case report and a review of the literature.
Published in:
Neurology & Clinical Neuroscience, 2015, v. 3, n. 3, p. 111, doi. 10.1111/ncn3.161
By:
- Yagi, Takuya;
- Shihashi, Gen;
- Oki, Koichi;
- Suzuki, Shigeaki;
- Shinoda, Masahiro;
- Itano, Osamu;
- Kitagawa, Yuko;
- Suzuki, Norihiro
Publication type:
Article
Production Test Considerations for Mixed-signal IC with Background Calibration.
Published in:
IEEJ Transactions on Electrical & Electronic Engineering, 2010, v. 5, n. 6, p. 627, doi. 10.1002/tee.20584
By:
- Yagi, Takuya;
- Kobayashi, Haruo;
- Tan, Yohei;
- Ito, Satoshi;
- Uemori, Satoshi;
- Takai, Nobukazu;
- Yamaguchi, Takahiro J.
Publication type:
Article
E2814: an anti‐tau therapy engages its CNS target and affects the downstream tangle‐specific biomarker MTBR‐tau243 in Dominantly Inherited Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082771
By:
- Zhou, Jin;
- Rawal, Sumit;
- Yagi, Takuya;
- Wildsmith, Kristin R;
- Takahashi, Eri;
- Horie, Kanta;
- Barthélemy, Nicolas R.;
- Aluri, Jagadeesh;
- Lalovic, Bojan;
- Boyd, Peter;
- Bateman, Randall J.;
- Reyderman, Larisa
Publication type:
Article
Safety, Pharmacokinetics and Immunogenicity of Single and Multiple Ascending Doses of the Anti‐Tau Therapeutic Antibody E2814: A Phase 1, First‐In‐Human (FIH) Study in Healthy Subjects.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082752
By:
- Rawal, Sumit;
- Yagi, Takuya;
- Boyd, Peter;
- Aluri, Jagadeesh;
- Wildsmith, Kristin R;
- Reyderman, Larisa
Publication type:
Article
First‐in‐Human (FIH), Single‐ and Multiple‐Ascending‐Dose (SAD/MAD) studies in healthy subjects of E2511, a novel tropomyosin receptor kinase a (TrkA) positive allosteric modulator (PAM).
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.066208
By:
- Aceves, Pau;
- Hall, Nancy;
- Dayal, Satish;
- Yagi, Takuya;
- Chang, Julia;
- Mikamoto, Masaki;
- Ringheim, Garth E;
- Takesuya, Tomioka;
- Hiramatsu, Naoki;
- Gordon, Robert;
- Giorgi, Luigi
Publication type:
Article
Absolute Bioavailability of a Single, Fixed Subcutaneous Dose of Lecanemab in Healthy Subjects.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.069438
By:
- Rawal, Sumit;
- Duong, Anh;
- Landry, Ishani;
- Aluri, Jagadeesh;
- Boyd, Peter;
- Yagi, Takuya;
- Swanson, Chad J;
- Reyderman, Larisa
Publication type:
Article
The design of Dominantly Inherited Alzheimer Disease Trial of the anti‐tau antibody, E‐2814, on the DIAN‐TU Tau Next Generation Platform.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.057320
By:
- Schneider, Lon S.;
- Bateman, Randall J.;
- Clifford, David B.;
- McDade, Eric;
- Wang, Guoqiao;
- Llibre‐Guerra, Jorge J.;
- Li, Yan;
- Mills, Susan;
- Santacruz, Anna;
- Sachdev, Pallavi;
- Li, David JianJun;
- O'Sullivan, Stacie;
- Yagi, Takuya;
- Koyama, Akihiko;
- Irizarry, Michael C.;
- Reyderman, Larisa
Publication type:
Article
Effectiveness of one-shot dual-energy subtraction chest radiography with flat-panel detector in distinguishing between calcified and non-calcified nodules.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-36785-y
By:
- Minato, Kojiro;
- Yamazaki, Motohiko;
- Yagi, Takuya;
- Hirata, Tetsuhiro;
- Tominaga, Masaki;
- You, Kyoryoku;
- Ishikawa, Hiroyuki
Publication type:
Article
First‐in‐Human Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E6742, a Dual Antagonist of Toll‐like Receptors 7 and 8, in Healthy Volunteers.
Published in:
Clinical Pharmacology in Drug Development, 2023, v. 12, n. 4, p. 363, doi. 10.1002/cpdd.1176
By:
- Yamakawa, Naoto;
- Tago, Fumitoshi;
- Nakai, Kenya;
- Kitahara, Yasumi;
- Ikari, Shingo;
- Hojo, Seiichiro;
- Hall, Nancy;
- Aluri, Jagadeesh;
- Hussein, Ziad;
- Gevorkyan, Hakop;
- Maruyama, Tatsuya;
- Ishizaka, Sally;
- Yagi, Takuya
Publication type:
Article
Establishment of Induced Pluripotent Stem Cells from Centenarians for Neurodegenerative Disease Research.
Published in:
PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041572
By:
- Yagi, Takuya;
- Kosakai, Arifumi;
- Ito, Daisuke;
- Okada, Yohei;
- Akamatsu, Wado;
- Nihei, Yoshihiro;
- Nabetani, Akira;
- Ishikawa, Fuyuki;
- Arai, Yasumichi;
- Hirose, Nobuyoshi;
- Okano, Hideyuki;
- Suzuki, Norihiro
Publication type:
Article
Pulmonary hypertension in an adult patient with congenital central hypoventilation syndrome: a case report.
Published in:
European Heart Journal Case Reports, 2024, v. 8, n. 3, p. 1, doi. 10.1093/ehjcr/ytae109
By:
- Terui, Yosuke;
- Ohura, Shoko;
- Nozaki, Tetsuji;
- Yagi, Takuya
Publication type:
Article
Density and function of inward currents in right atrial cells from chronically fibrillating canine atria
Published in:
Cardiovascular Research, 2002, v. 54, n. 2, p. 405, doi. 10.1016/S0008-6363(02)00279-1
By:
- Yagi, Takuya;
- Pu, Jielin;
- Chandra, Parag;
- Hara, Motoki;
- Danilo Jr., Peter;
- Rosen, Michael R.;
- Boyden, Penelope A.
Publication type:
Article
Diagnostic accuracy of neuropsychological tests for classification of dementia.
Published in:
Neurology Asia, 2016, v. 21, n. 1, p. 47
By:
- Takuya Yagi;
- Daisuke Ito;
- Daisuke Sugiyama;
- Satoko Iwasawa;
- Hajime Tabuchi;
- Mika Konishi;
- Machiko Araki;
- Naho Saitoh;
- Yoshihiro Nihei;
- Masaru Mimura;
- Norihiro Suzuki
Publication type:
Article
Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation.
Published in:
Human Molecular Genetics, 2016, v. 25, n. 9, p. 1803, doi. 10.1093/hmg/ddw052
By:
- Kohsuke Kanekura;
- Takuya Yagi;
- Cammack, Alexander J.;
- Mahadevan, Jana;
- Masahiko Kuroda;
- Harms, Matthew B.;
- Miller, Timothy M.;
- Urano, Fumihiko
Publication type:
Article
Evidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis.
Published in:
Human Molecular Genetics, 2015, v. 24, n. 6, p. 1617, doi. 10.1093/hmg/ddu575
By:
- Osaka, Mayuko;
- Ito, Daisuke;
- Yagi, Takuya;
- Nihei, Yoshihiro;
- Suzuki, Norihiro
Publication type:
Article
Characterization of inclusion bodies with cytoprotective properties formed by seipinopathy-linked mutant seipin.
Published in:
Human Molecular Genetics, 2012, v. 21, n. 3, p. 635, doi. 10.1093/hmg/ddr497
By:
- Ito, Daisuke;
- Yagi, Takuya;
- Ikawa, Masahito;
- Suzuki, Norihiro
Publication type:
Article
Modeling familial Alzheimer's disease with induced pluripotent stem cells.
Published in:
Human Molecular Genetics, 2011, v. 20, n. 23, p. 4530, doi. 10.1093/hmg/ddr394
By:
- Yagi, Takuya;
- Ito, Daisuke;
- Okada, Yohei;
- Akamatsu, Wado;
- Nihei, Yoshihiro;
- Yoshizaki, Takahito;
- Yamanaka, Shinya;
- Okano, Hideyuki;
- Suzuki, Norihiro
Publication type:
Article
N88S seipin mutant transgenic mice develop features of seipinopathy/BSCL2-related motor neuron disease via endoplasmic reticulum stress.
Published in:
Human Molecular Genetics, 2011, v. 20, n. 19, p. 3831, doi. 10.1093/hmg/ddr304
By:
- Yagi, Takuya;
- Ito, Daisuke;
- Nihei, Yoshihiro;
- Ishihara, Tadayuki;
- Suzuki, Norihiro
Publication type:
Article
Increasing Microbleeds in CADASIL.
Published in:
European Neurology, 2013, v. 69, n. 6, p. 352, doi. 10.1159/000348720
By:
- Yagi, Takuya;
- Konoeda, Fumie;
- Mizuta, Ikuko;
- Mizuno, Toshiki;
- Suzuki, Norihiro
Publication type:
Article
Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue.
Published in:
Molecular Brain, 2012, v. 5, n. 1, p. 35, doi. 10.1186/1756-6606-5-35
By:
- Yoichi Imaizumi;
- Yohei Okada;
- Wado Akamatsu;
- Masato Koike;
- Naoko Kuzumaki;
- Hideki Hayakawa;
- Tomoko Nihira;
- Tetsuro Kobayashi;
- Manabu Ohyama;
- Shigeto Sato;
- Masashi Takanashi;
- Manabu Funayama;
- Akiyoshi Hirayama;
- Tomoyoshi Soga;
- Takako Hishiki;
- Makoto Suematsu;
- Takuya Yagi;
- Daisuke Ito;
- Arifumi Kosakai;
- Kozo Hayashi
Publication type:
Article
Identification of prognostic factors to predict cognitive decline of patients with early Alzheimer's disease in the Japanese Alzheimer's Disease Neuroimaging Initiative study.
Published in:
Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2019, v. 5, n. 1, p. 364, doi. 10.1016/j.trci.2019.06.004
By:
- Yagi, Takuya;
- Kanekiyo, Michio;
- Ito, Junichi;
- Ihara, Ryoko;
- Suzuki, Kazushi;
- Iwata, Atsushi;
- Iwatsubo, Takeshi;
- Aoshima, Ken
Publication type:
Article
Coronary computed tomography angiography using 128-slice dual-source computed tomography in patients with severe calcification.
Published in:
2017
By:
- Sato, Suguru;
- Horii, Yosuke;
- Yoshimura, Norihiko;
- Yagi, Takuya;
- Aoyama, Hidefumi
Publication type:
journal article
A Sodium Channel Blocker, Pilsicainide, Produces Atrial Post-Repolarization Refractoriness through the Reduction of Sodium Channel Availability.
Published in:
Tohoku Journal of Experimental Medicine, 2011, v. 225, n. 1, p. 35, doi. 10.1620/tjem.225.35
By:
- Fukuda, Koji;
- Watanabe, Jun;
- Yagi, Takuya;
- Wakayama, Yuji;
- Nakano, Makoto;
- Kondo, Masateru;
- Kumagai, Koji;
- Miura, Masahito;
- Shirato, Kunio;
- Shimokawa, Hiroaki
Publication type:
Article
Characterization of membrane penetration and cytotoxicity of C9orf72-encoding arginine-rich dipeptides.
Published in:
Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31096-z
By:
- Kanekura, Kohsuke;
- Harada, Yuichiro;
- Fujimoto, Mao;
- Yagi, Takuya;
- Hayamizu, Yuhei;
- Nagaoka, Kentaro;
- Kuroda, Masahiko
Publication type:
Article
Identification of compounds that preferentially suppress the growth of T‐cell acute lymphoblastic leukemia‐derived cells.
Published in:
Cancer Science, 2023, v. 114, n. 10, p. 4032, doi. 10.1111/cas.15918
By:
- Miyashita, Kazuya;
- Yagi, Takuya;
- Kagaya, Noritaka;
- Takechi, Azusa;
- Nakata, Chihiro;
- Kanda, Risa;
- Nuriya, Hideko;
- Tanegashima, Kosuke;
- Hoyano, Shota;
- Seki, Fumiya;
- Yoshida, Chihiro;
- Hachiro, Yoshifumi;
- Higashi, Tomoya;
- Kitada, Nobuo;
- Toya, Takashi;
- Kobayashi, Takeshi;
- Najima, Yuho;
- Goyama, Susumu;
- Maki, Shojiro A.;
- Kitamura, Toshio
Publication type:
Article
Screening and follow‐up of chronic liver diseases with understanding their etiology in clinics and hospitals.
Published in:
JGH Open, 2020, v. 4, n. 5, p. 827, doi. 10.1002/jgh3.12406
By:
- Ogawa, Masahiro;
- Tsuchiya, Atsunori;
- Watanabe, Takayuki;
- Setsu, Toru;
- Kimura, Naruhiro;
- Matsuda, Masato;
- Hoshiyama, Yoshiki;
- Saito, Hiroaki;
- Kanazawa, Tsutomu;
- Shiotani, Motoi;
- Sato, Tatsuhiko;
- Yagi, Takuya;
- Igarashi, Koji;
- Yoshimura, Norihiko;
- Takamura, Masaaki;
- Aoyama, Hidefumi;
- Terai, Shuji
Publication type:
Article
HRCT texture analysis for pure or part-solid ground-glass nodules: distinguishability of adenocarcinoma in situ or minimally invasive adenocarcinoma from invasive adenocarcinoma.
Published in:
2018
By:
- Yagi, Takuya;
- Yamazaki, Motohiko;
- Ohashi, Riuko;
- Ogawa, Rei;
- Ishikawa, Hiroyuki;
- Yoshimura, Norihiko;
- Tsuchida, Masanori;
- Ajioka, Yoichi;
- Aoyama, Hidefumi
Publication type:
journal article
345-LB: Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF): A New Therapeutic Target for Wolfram Syndrome.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-345-LB
By:
- MORIKAWA, SHUNTARO;
- MAHADEVAN, JANA;
- YAGI, TAKUYA;
- ABREU, DAMIEN;
- KANEKURA, KOHSUKE;
- BROWN, CRIS M.;
- URANO, FUMIHIKO
Publication type:
Article

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