N-{2[((1 Z)-1-{[(2, 6-dimethylphenyl)amino]carbonyl}-3-oxo-3-arylprop-1-en-1-yl)amino]ethyl}- N, N-dimethyl- 1-oxoethanaminium chlorides were synthesized by acylation of arylpyruvic acid enaminoamides. Compounds with high local-anesthetic activity were found among them.