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- Title
Accurate identification of orthologous segments among multiple genomes.
- Authors
Hachiya, Tsuyoshi; Osana, Yasunori; Popendorf, Kris; Sakakibara, Yasubumi
- Abstract
Motivation: The accurate detection of orthologous segments (also referred to as syntenic segments) plays a key role in comparative genomics, as it is useful for inferring genome rearrangement scenarios and computing whole-genome alignments. Although a number of algorithms for detecting orthologous segments have been proposed, none of them contain a framework for optimizing their parameter values.
- Subjects
GENOMES; GENOMICS; MOLECULAR genetics; GENETIC research; ALGORITHMS
- Publication
Bioinformatics, 2009, Vol 25, Issue 7, p853
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/btp070