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- Title
Impact of Lowering the Screening Age for Colorectal Cancer on Early Diagnosis and Treatment: A Retrospective Study in a Turkish Cohort.
- Authors
Ofluoğlu, Cem Batuhan; Mülküt, Fırat; Altıntaş, Mehmet Mustafa; Çevik, Ayhan
- Abstract
Objective: This study was planned in line with the American Cancer Society’s recommendation to lower the colorectal cancer (CRC) screening age from 50 to 45. The study aims to evaluate the results of colonoscopic polypectomy in patients aged 45-49 in Türkiye, examining the prevalence and characteristics of colorectal polyps and malignancies, with the goal of establishing a database for Türkiye. Methods: Colonoscopies in the endoscopy unit of our hospital between September 2020 and September 2023 were retrospectively examined. Patients aged 45-49 diagnosed with polyps or malignancies were included. Exclusions were made for patients who were unreachable, unable to complete a full colonoscopy, underwent the procedure for screening purposes, had a history of malignancy, suffered from polyp syndromes, or were under surveillance following a prior colonoscopy. We analyzed demographic information, indications for colonoscopy, and pathological findings. Statistical analyses were carried out using SPSS version 25.0, with a p-value of <0.05 considered statistically significant. Results: From 748 patients, 106 with detected polyps or malignancy were included. Most patients were male (56.6%), with an average age of 47.07±1.52. Key colonoscopy indications were benign perianal diseases (34%), changes in bowel habits (27.4%), and anemia (12.3%). The majority of polyps were located in the left colon and rectum, predominantly low-grade dysplasia adenomas (68.9%) and high-grade dysplasia adenomas (9.4%). The polyp detection rate was 14.2%, and the malignancy rate was 2.8%. Conclusion: According to the literature, the rate of polyp and malignancy detection in colonoscopies performed as part of the screening program for people aged 50 and over is similar to the rates found in our study. Based on this similarity, it may be appropriate to consider including patients in the 45-50 age group in the screening scope.
- Subjects
TURKEY; POLYPECTOMY; MEDICAL screening; COLORECTAL cancer; VIRTUAL colonoscopy; AMERICAN Cancer Society Inc.; COLON polyps; CANCER diagnosis; EARLY diagnosis; AGE groups
- Publication
Southern Clinics of Istanbul Eurasia, 2024, Vol 35, Issue 1, p34
- ISSN
2587-0998
- Publication type
Article
- DOI
10.14744/scie.2024.45762