We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Synthesis and antifungal activity of new dihydrofurocoumarins and dihydrofuroquinolines.
- Authors
USTALAR, Aslı; YILMAZ, Mehmet; OSMANİ, Agim; Aşkın^KEÇELİ, Sema
- Abstract
We investigated the radical addition of 4-hydroxycoumarin (1a) and 4-hydroxyquinoline (1b) with conjugated dienes (2a-f) mediated by cerium(IV) ammonium nitrate (CAN) resulting in ethenyl substituted 2,3-dihydrofurocoumarin (3a-f) and 3,5-dihydrofuroquinoline (3g, 3h) compounds in moderate to good yields. All compounds were characterized by spectroscopic methods (IR, MS, and 1H and 13C NMR) and microanalysis. Antifungal activities of these compounds were investigated against the fungi Candida albicans, C. parapsilosis, C. krusei, C. glabrata, C. tropicalis, and Aspergillus fumigatus.
- Subjects
DIHYDROFURANS; ANTIFUNGAL agents; CERIUM oxides; AMMONIUM nitrate; CANDIDA albicans; ASPERGILLUS fumigatus; NUCLEAR magnetic resonance
- Publication
Turkish Journal of Chemistry, 2017, Vol 41, Issue 1, p80
- ISSN
1300-0527
- Publication type
Article
- DOI
10.3906/kim-1604-22