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- Title
Vitamin D receptor activation: cardiovascular and renal implications.
- Authors
Nigwekar, Sagar U; Thadhani, Ravi
- Abstract
The effects of vitamin D receptor activation on cardiovascular diseases, especially hypertension and cardiac dysfunction, are areas of active investigation. This article reviews the current state of knowledge about vitamin D receptor activation with respect to blood pressure, heart, and vascular health, as well as to chronic kidney disease and end-stage renal disease. Potential biological mechanisms, the role of vitamin D-binding protein, and data from observational and randomized controlled trials on this topic are summarized.
- Subjects
HEART physiology; CHRONIC kidney failure complications; BLOOD pressure; CARDIOVASCULAR diseases; CELL receptors; DIETARY supplements; KIDNEY diseases; VITAMIN D
- Publication
Kidney International Supplements, 2013, Vol 3, Issue 5, p427
- ISSN
2157-1724
- Publication type
Article
- DOI
10.1038/kisup.2013.89