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- Title
A Woman with Tuberculosis Multidrug Resistance and QTc Prolongation Repetitive Interval: A Case Report.
- Authors
Tutik Kusmiati; Ni Made Mertaniasih; Johanes Nugroho Eko Putranto; Budi Suprapti; Soedarsono; Bahmid, Abdul Rahman
- Abstract
Background: Prolonged QTc interval is one of the side effects of the short-regimen MDR-TB. QTc prolongation is a risk factor for Torsades de pointes and is influenced by many factors. Case: 47-year-old woman who was diagnosed with MDR-TB through GeneXpert examination and received short-regimen MDR-TB. This patient experienced repeated QTc prolongation, with peak QTc interval 600 msec occurring at 4th month with mild hypokalemia without clinical symptoms. The patient completed 9 months of shortregimen therapy with improve chest x ray followed by negative sputum culture. Conclusion: Short-regimen MDR-TB contains several drugs that cause QTc prolongation. Clinical evaluation is required in patients with QTc prolongation before changing the regiment.
- Subjects
VENTRICULAR tachycardia; TUBERCULOSIS; MULTIDRUG resistance; CHEST X rays; SYMPTOMS; DIAGNOSIS
- Publication
Indian Journal of Forensic Medicine & Toxicology, 2021, Vol 15, Issue 4, p2748
- ISSN
0973-9122
- Publication type
Case Study
- DOI
10.37506/ijfmt.v15i4.17119