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- Title
Down-regulation of interferon-γ signaling by gene transfer of Stat1 mutant in mesangial cells.
- Authors
Sakatsume, Minoru; Narita, Ichiei; Yamazaki, Hajime; Saito, Akihiko; Nakagawa, Yoichi; Kuriyama, Hideyuki; Kuwano, Ryozo; Gejyo, Fumitake; Arakawa, Masaaki
- Abstract
Investigates the role of Interferon-gamma (IFN) in the activation of Stat1 alpha in mesangial cells. Secretion of IFN-gamma by T lymphocytes and natural killer cells; Importance of gene transfer in IFN-gamma signal transduction regulation; Use of the Western blot for Stat1 messenger RNA detection.
- Subjects
INTERFERONS; T cells; KILLER cells; GENETIC transformation
- Publication
Kidney International, 2000, Vol 57, Issue 2, p455
- ISSN
0085-2538
- Publication type
Article
- DOI
10.1046/j.1523-1755.2000.00865.x