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- Title
Azotemia and Mortality among Babesia microti-Like Infected Dogs.
- Authors
Camacho, A. Tomas; Guitian, F. Javier; Pallas, Estrella; Gestal, Juan Jesus; Olmeda, A. Sonia; Goethert, Heidi K.; III, Sam R. Telford; Spielman, Andrew
- Abstract
Babesia microti-like piroplasms are a recently recognized cause of illness in dogs in northwest Spain. Our objective was to describe the clinical characteristics and investigate the risk factors for azotemia and death among 58 B microti-like infected dogs. Twenty-one of the 58 (36%) dogs were azotemic at the time that the infection was diagnosed. The case fatality rate during the following week was 22%. Dogs with azotemia at the time of diagnosis were 10 times (95% CI, 3.26-28.8) more likely to die during the following week. Azotemia was the main cause of death for B microti-like infected dogs (attributable fraction = 90%). Severe anemia was present in 45 of the 58 (78%) dogs. Azotemic dogs also presented with hyperphosphatemia, hypoalbuminemia, hypercholesterolemia, proteinuria, and high urine protein: creatinine ratios, suggesting a glomerular component to the disease. Age was the only factor significantly associated with the risk of azotemia (P = .042): on average, a 4-year age increase doubled the risk of an infected dog being azotemic. The only factor significantly associated with mortality was azotemia (P = .001). We concluded that B microti-like infection is associated with a high risk of azotemia and mortality.
- Publication
Journal of Veterinary Internal Medicine, 2004, Vol 18, Issue 2, p141
- ISSN
0891-6640
- Publication type
Article
- DOI
10.1111/j.1939-1676.2004.tb00152.x