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- Title
Anti-factor H autoantibody-associated hemolytic uremic syndrome: the earlier diagnosed and treated, the better.
- Authors
Loirat, Chantal; Frémeaux-Bacchi, Véronique
- Abstract
Atypical hemolytic uremic syndrome (HUS) secondary to anti-factor H autoantibodies has a poor prognosis. The study by Sinha et al. of a large cohort of Indian children makes a substantial contribution to improved management of this form of HUS by showing that standardized titration of anti-factor H autoantibodies is applicable worldwide and that early treatment initiation and guidance of maintenance treatment by autoantibody titer monitoring significantly improve outcomes.
- Subjects
HEMOLYTIC-uremic syndrome; AUTOANTIBODIES; IMMUNOGLOBULINS; VOLUMETRIC analysis; CHROMOSOME polymorphism
- Publication
Kidney International, 2014, Vol 85, Issue 5, p1019
- ISSN
0085-2538
- Publication type
Article
- DOI
10.1038/ki.2013.447