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- Title
Recurrent hemolytic uremic syndrome in the renal allograft.
- Authors
Nasr, S. H.; Brouder, D.; Haider, N.; Markowitz, G. S.
- Abstract
The article discusses repeated hemolytic uremic syndrome in the renal allograft. The author illustrated the case of a Caucasian woman with double vision, uncontrolled hypertension, anemia, thrombocytopenia and acute renal failure who was later found to have an elevated lactate dehydrogenase level and schistocytes on a peripheral blood smear. Renal biopsy revealed acute and severe changes of thrombotic microangiopathy, with abundant glomerular and vascular fibrin thrombi. Despite being treated with high-dose steroids and plasmapheresis, she did not recover renal function, thus the renal transplantation. Months later, renal allograft biopsy revealed nearly identical results to those seen in the previous, native renal biopsy.
- Subjects
HEMOLYTIC-uremic syndrome; KIDNEY transplantation; THROMBOCYTOPENIA; ACUTE kidney failure; HOMOGRAFTS; DEHYDROGENASES; RENAL biopsy; THROMBOTIC thrombocytopenic purpura; STEROID drugs; PLASMAPHERESIS
- Publication
Kidney International, 2006, Vol 69, Issue 6, p949
- ISSN
0085-2538
- Publication type
Article
- DOI
10.1038/sj.ki.5000287