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- Title
Teixobactin: A Powerful Tool for Combating Resistant Strains.
- Authors
RAWAL, TEJAL; BUTANI, SHITAL
- Abstract
Resistance to antibiotics has grown out to be a serious health concern. Despite this serious health crisis, no new antibiotics have been discovered since the last 30 years. A new ray of hope in the form of teixobactin has come out of the dark, which could demonstrate the potential to be effective in countering resistance. This new antibiotic has an interesting mechanism of action against bacteria. The discovery of this wonderful compound has evolved as a major breakthrough especially in this era of antibiotic catastrophe. This review article highlights various facets of teixobactin that include chemistry, mode of action, in vitro and in vivo activities. Though the compound has not yet undergone clinical studies, its effect on mice models has given hope for overpowering resistance. This review attempts to provide information about teixobactin and its potential for fighting as antibiotic resistance.
- Subjects
ANTIBIOTICS; DRUG resistance; PUBLIC health; ANTIBACTERIAL agents; ANTI-infective agents
- Publication
Indian Journal of Pharmaceutical Sciences, 2016, Vol 78, Issue 6, p697
- ISSN
0250-474X
- Publication type
Article
- DOI
10.4172/pharmaceutical-sciences.1000172