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- Title
Responses of Endothelial Progenitor Cells to Chronic and Acute Physical Activity in Healthy Individuals.
- Authors
Tkacz, Marta; Zgutka, Katarzyna; Tomasiak, Patrycja; Tarnowski, Maciej
- Abstract
Endothelial progenitor cells (EPCs) are circulating cells of various origins that possess the capacity for renewing and regenerating the endothelial lining of blood vessels. During physical activity, in response to factors such as hypoxia, changes in osmotic pressure, and mechanical forces, endothelial cells undergo intense physiological stress that results in endothelial damage. Circulating EPCs participate in blood vessel repair and vascular healing mainly through paracrine signalling. Furthermore, physical activity may play an important role in mobilising this important cell population. In this narrative review, we summarise the current knowledge on the biology of EPCs, including their characteristics, assessment, and mobilisation in response to both chronic and acute physical activity in healthy individuals.
- Subjects
PHYSICAL activity; PROGENITOR cells; ENDOTHELIAL cells; OSMOTIC pressure; PHYSIOLOGICAL stress
- Publication
International Journal of Molecular Sciences, 2024, Vol 25, Issue 11, p6085
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms25116085