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- Title
Health-related quality of life of children and adolescents with cerebral palsy in low- and middle-income countries: a systematic review.
- Authors
Power, Rosalie; King, Catherine; Muhit, Mohammad; Heanoy, Eamin; Galea, Claire; Jones, Cheryl; Badawi, Nadia; Khandaker, Gulam
- Abstract
<bold>Aim: </bold>To systematically review literature on health-related quality of life (HRQoL) of children and adolescents (≤18yo) with cerebral palsy (CP) from low- and middle-income countries (LMICs) to identify trends in HRQoL and areas for future research.<bold>Method: </bold>We systematically reviewed six key bibliographic databases and two reviewers independently screened results. Peer-reviewed original articles examining HRQoL of children from LMICs were eligible.<bold>Results: </bold>A total of 22 524 papers were identified, of which 16, from eight LMICs, were included. Four measures of HRQoL were used; Child Health Questionnaire Parent Form 50 (n=5); Paediatric Quality of Life Inventory 3.0 and 4.0 (n=4); CP Quality of Life Questionnaire for Children (n=4); Lifestyle Assessment Questionnaire CP (n=3). Children with CP from LMICs (n=1579; 2-18y) had significantly poorer HRQoL on all instrument dimensions when compared to age-matched controls (p<0.003) and on all except two dimensions when compared to peers in high-income countries (p<0.001). Physical well-being dimensions of HRQoL were poorest overall and associated with impaired motor function.<bold>Interpretation: </bold>Research to improve HRQoL in LMICs is required and should address all aspects of HRQoL. Future research is recommended to incorporate multi-respondent assessment, utilize both general and CP-specific measures of HRQoL, and delineate adolescents as a unique cohort. What this paper adds Children with cerebral palsy from low- and middle-income countries are at high risk of poor health-related quality of life (HRQoL). Physical well-being was poorest dimension of HRQoL and associated with impaired motor function.
- Subjects
CHILDREN with cerebral palsy; DEVELOPMENTAL disabilities; CHILD development; CEREBRAL palsy; PEDIATRIC neurology; DIAGNOSIS; POVERTY &; psychology; MENTAL health; QUALITY of life; QUESTIONNAIRES; SYSTEMATIC reviews; BIBLIOGRAPHIC databases; PSYCHOLOGY
- Publication
Developmental Medicine & Child Neurology, 2018, Vol 60, Issue 5, p469
- ISSN
0012-1622
- Publication type
journal article
- DOI
10.1111/dmcn.13681