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- Title
One hundred years of peptide chemistry.
- Authors
Suresh Babu, V. V.
- Abstract
Emil Fischer is considered to be the founding father of the field of peptide chemistry and originator of the term peptide. In the beginning of the 20th century, Fischer had a clear vision to foresee the day when a protein would be synthesized. Subsequent to this brilliant beginning, progress however was slow for the next 50 years. In 1953, the chemical synthesis of oxytocin by duVigneaud was a landmark achievement. The subsequent decades witnessed the discovery of a vast number of biologically active peptides. The last three decades saw development of multiple simultaneous syntheses, peptide libraries and peptide vaccines. This article is a concise account of the types of peptides discovered and their biological role.
- Subjects
FISCHER, Emil, 1852-1919; PEPTIDE synthesis; OXYTOCIN; AMINO acids; CHEMICAL reactions
- Publication
Resonance: Journal of Science Education, 2011, Vol 16, Issue 7, p640
- ISSN
0971-8044
- Publication type
Article
- DOI
10.1007/s12045-011-0071-7