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- Title
A novel calcium-dependent proapoptotic effect of annexin 1 on human neutrophils¹.
- Authors
Solita, Egle; Kamal, Ahmad; Russo-Marie, Francoise; Buckingham, Julia C.; Marullo, Stefano; Perretti, Mauro
- Abstract
Investigates the effects of human recombinant glucocorticoid-regulated protein annexin 1 (ANXA1) on several markers of in vitro process of neutrophil (PMN) activation with particular emphasis on a novel biological activity of this protein, induction of a calcium-dependent early apoptotic signal. Analysis of ANXAI effects on several parameters of PMN activation; Association of annexin 1-induced PMN activation with accelerated cell apoptosis; Conclusions.
- Subjects
GLUCOCORTICOIDS; PROTEINS; ANNEXINS; NEUTROPHILS; CALMODULIN; APOPTOSIS
- Publication
FASEB Journal, 2003, Vol 17, Issue 11, p1544
- ISSN
0892-6638
- Publication type
Article
- DOI
10.1096/fj.02-0941fje