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- Title
Residual Ethylene Oxide in Medical Devices: Effects and Estimation Methods, an Overview.
- Authors
Sreejith, Lathikumari Sasidharan; Sasi, Renjith
- Abstract
Medical devices play a crucial role in the day-to-day lives of human beings as a tool for the diagnosis, detection, imaging and treatment of various benign/malignant conditions of human body. Sterilization of medical devices is inevitable as it will rule out any possible invasion of pathogenic microorganisms to the immunologically compromised patients. Ethylene Oxide (EtO) route is one of the most appreciated sterilization methods due to its convenient and cost-effective operation and suitability for soft polymeric medical devices. Even though it's convenient, the residual EtO having carcinogenic, mutagenic and teratogenic activity poses a serious threat to the patients. Hence, the estimation of residual EtO is one of the unavoidable quality tests one should perform before using any medical devices sterilized with EtO. This article intended to give an overview of the physiological effects of EtO and various methods adopted for the estimation of residual EtO in sterilized specimens.
- Subjects
ETHYLENE oxide; MEDICAL equipment; MICROBIAL invasiveness; HUMAN body; HUMAN beings
- Publication
Trends in Biomaterials & Artificial Organs, 2020, Vol 34, Issue 1, p7
- ISSN
0971-1198
- Publication type
Article