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- Title
Konsensusempfehlungen zur Diagnose und Therapie der Hyponatriämie der Österreichischen Gesellschaft für Nephrologie 2024.
- Authors
Schwarz, Christoph; Lindner, Gregor; Windpessl, Martin; Knechtelsdorfer, Maarten; Saemann, Marcus D.
- Abstract
Summary: Hyponatremia is a disorder of water homeostasis. Water balance is maintained by the collaboration of renal function and cerebral structures, which regulate thirst mechanisms and secretion of the antidiuretic hormone. Measurement of serum-osmolality, urine osmolality and urine-sodium concentration help to diagnose the different reasons for hyponatremia. Hyponatremia induces cerebral edema and might lead to severe neurological symptoms, which need acute therapy. Also, mild forms of hyponatremia should be treated causally, or at least symptomatically. An inadequate fast increase of the serum sodium level should be avoided, because it raises the risk of cerebral osmotic demyelination. Basic pathophysiological knowledge is necessary to identify the different reasons for hyponatremia which need different therapeutic procedures.
- Subjects
CEREBRAL edema; VASOPRESSIN; OSMOLALITY; DEMYELINATION; POLYDIPSIA
- Publication
Wiener Klinische Wochenschrift, 2024, Vol 136, Issue 1, p1
- ISSN
0043-5325
- Publication type
Article
- DOI
10.1007/s00508-024-02325-5