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- Title
Modern stem cell therapy: approach to disease.
- Authors
Zemljic, Mateja; Pejkovic, Bozena; Krajnc, Ivan; Kocbek, Lidija
- Abstract
Various types of stem cells exist, each with their own advantages and disadvantages. Considering the current available evidence, important preclinical and clinical studies regarding the therapeutic potential of stem cells, stem cell therapy might be the important strategy for tissue repair. The development of stem cell therapy for tissue repair has primarily relied on stem cells, especially mesenchymal stem cells. Multilineage differentiation into all of the described cells are considered as important candidates for a range of diseases like neurological diseases, cardiovascular diseases, gastrointestinal cancer and genetic defects, as well as for acute and chronic wounds healing and pharmaceutical treatment. We review the properties and multipotency of stem cells and their differentiation potential, once cultured under specific growth conditions, for use in cell-based therapies and functional tissue replacement.
- Subjects
STEM cell treatment; MESENCHYMAL stem cells; CELL differentiation; CELL culture; TREATMENT effectiveness
- Publication
Wiener Klinische Wochenschrift, 2015, Vol 127, p199
- ISSN
0043-5325
- Publication type
Article
- DOI
10.1007/s00508-015-0903-7