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- Title
Lymphoproliferative response and its relationship with histological lesions in experimental ovine paratuberculosis and its diagnostic implications.
- Authors
N. Kurade; B. Tripathi
- Abstract
Abstract  Lymphoproliferative response (LPR) was studied in 19 lambs orally infected (Group I) with Mycobacterium avium subsp. paratuberculosis (MAP) with in vitro lymphocyte stimulation test using MTT dye reduction assay. The non-specific LPR against Con A and specific LPR against sonicated antigen and johnin PPD (purified protein derivatives) were estimated on preinfection (0 day) and various days postinfection period (15 to 330 dpi) in the animals, which were classified according to histological and bacteriological evidence of paratuberculosis infection. Of the two antigens used, johnin PPD was found to be superior in terms of consistency and uniformity of response over an observation period of about a year. Significantly (Pâ
- Subjects
MYCOBACTERIAL diseases in animals; PARATUBERCULOSIS; MYCOBACTERIUM; MYCOBACTERIUM avium
- Publication
Veterinary Research Communications, 2008, Vol 32, Issue 1, p107
- ISSN
0165-7380
- Publication type
Article
- DOI
10.1007/s11259-007-9008-8