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- Title
Vaccines for Influenza.
- Authors
Tsilibary, Effie-Photini; Charonis, Spyros A.; Georgopoulos, Apostolos P.
- Abstract
Two reviews by Harding and Heaton [[1]] and Lewnard and Cobey [[2]] shed light on recent progress and new developments towards a universal influenza vaccine and the effectiveness of the influenza vaccine. For vaccine effectiveness, the required information is the reduction a vaccine confers to an individual's susceptibility to influenza infection or influenza-caused illness compared to the same individual's susceptibility without the vaccine. The all-or-nothing vaccine effect which is considered here takes into account that a fraction of recipients respond to the vaccine and are perfectly protected, whereas the susceptibility of other recipients is unaffected by vaccination; however, it does not recover a "leaky" vaccine effect, under which vaccine responders have incomplete protection. There is difficulty in determining how effective the influenza vaccine may be; however, studies have shown that the influenza vaccine prevented an estimated 7 million illnesses, 3.7 million medical visits, 109,000 hospitalizations, and 8000 deaths associated with influenza during the 2017-2018 season [[7]].
- Subjects
INFLUENZA vaccines; BACTERIAL vaccines; HERPES zoster vaccines; RHINOVIRUSES; DNA vaccines; FLU vaccine efficacy; VACCINATION complications; HLA histocompatibility antigens
- Publication
Vaccines, 2021, Vol 9, Issue 1, p47
- ISSN
2076-393X
- Publication type
Editorial
- DOI
10.3390/vaccines9010047