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- Title
Development of cytomegalovirus resistant to maribavir: real world, real problem?
- Authors
Kleiboeker, Hanna L.; Prom, Alyson; Paplaczyk, Krista
- Abstract
This article discusses a case report of a lung transplant recipient who developed multi-drug resistant cytomegalovirus (CMV), including resistance to ganciclovir (GCV) and maribavir (MARI). The patient received various antiviral treatments, including valganciclovir (VGC), cidofovir (CDV), and foscarnet (FOS), but experienced adverse effects and fluctuating CMV viral load. The case highlights the emerging issue of MARI resistance in solid organ transplant recipients and the challenges in managing CMV infections in this population. The document also discusses the risks and considerations associated with the use of MARI, including the need for careful initiation and monitoring for resistance. The authors emphasize the need for further research on the effectiveness and nuances of MARI as a treatment for CMV infections.
- Subjects
CYTOMEGALOVIRUSES; CYTOMEGALOVIRUS diseases
- Publication
Transplant Infectious Disease, 2024, Vol 26, Issue 2, p1
- ISSN
1398-2273
- Publication type
Article
- DOI
10.1111/tid.14259