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- Title
The Effects of a Single Dialysis Session on Atrial Electromechanical Conduction Times and Functions.
- Authors
Tekce, Hikmet; Ozturk, Serkan; aktas, Gulali; Tekce, Buket Kin; Erdem, alim; Ozyasar, Mehmet; Duman, Tuba Taslamacıoglu; Yazici, Mehmet
- Abstract
Background/Aims: Abnormalities in atrial electromechanical delay (EMD) times and mechanical functions are considered as independent predictors of atrial fibrillation. However, to date, effects of a single hemodialysis (HD) session and acute volume-preload changes on atrial-EMD functions have not been investigated by Tissue Doppler Echocardiography (TDE). The aim of the present study was to evaluate atrial-EMD times and mechanical functions in HD patients. Methods: Thirty-five non-diabetic, normotensive HD patients and 35 healthy control subjects were enrolled in the study. Standard and TDE performed before mid-week dialysis session for hemodialysis group and on admission for control group. Results: Interatrial and left-right intraatrial-EMD intervals and left atrial mechanical volumes were significantly longer in hemodialysis group compared to controls (all p<0.01) and were reduced after HD session. Furthermore, removed ultrafiltration volume was associated with reduction in atrial-EMD intervals and functional volumes. LA-passive emptying volume, ultrafiltration volume, LV-E/E' ratio, and Vp were independent predictors of interatrial-EMD. Conclusions: The present study confirms negative effects in HD patients of structural remodeling and reveals negative effects of electrical remodeling. Prolonged inter and intraatrial-EMD intervals should be the underlying pathophysiological factors of increased rate of atrial fibrillation in the HD population. © 2014 S. Karger AG, Basel
- Subjects
ATRIAL fibrillation; HEMODIALYSIS; DOPPLER echocardiography; CONTROL groups; PATHOLOGICAL physiology
- Publication
Kidney & Blood Pressure Research, 2013, Vol 37, Issue 6, p622
- ISSN
1420-4096
- Publication type
Article
- DOI
10.1159/000355742