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- Title
FORMULATION AND EVALUATION OF LAMOTRIGINE ORALLY DISINTEGRATING TABLETS TO MASK THE BITTER TASTE AND TO IMPROVE THE DRUG RELEASE.
- Authors
Gangavarapu, Pavan Kumar; Prasad, G. S.
- Abstract
The aim of the present study was to formulate the Lamotrigine Orally Disintegrating Tablets by wet granulation process using Stearic acid, Eudragit EPO and Mannitol slurry to mask the bitter taste and to improve the drug release of Lamotrigine. Trial batches were formulated and evaluated using different concentrations of excipients to match the reference product dissolution profile.
- Subjects
LAMOTRIGINE; DRUG administration; DRUG tablets; STEARIC acid; DISSOLUTION (Chemistry)
- Publication
International Journal of Pharmacology & Biological Sciences, 2012, Vol 6, Issue 3, p25
- ISSN
0973-6808
- Publication type
Article