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- Title
Optimal Management of Severe/Refractory Asthma.
- Authors
Pakhale, Smita; Mulpuru, Sunita; Boyd, Matthew
- Abstract
Asthma is a chronic inflammatory disease of the airways, affecting approximately 300 million people worldwide. Asthma results in airway hyperresponsiveness, leading to paroxysmal symptoms of wheeze, cough, shortness of breath, and chest tightness. When these symptoms remain uncontrolled, despite treatment with high doses of inhaled and ingested corticosteroids, asthmatic patients are predisposed to greater morbidity and require more health care support. Treating patients with severe asthma can be difficult and often poses a challenge to physicians when providing ongoing management. This clinical review aims to discuss the definition, prevalence and evaluation of severe asthmatics, and provides a review of the existing pharmacologic and non-pharmacologic treatment options.
- Subjects
ADRENERGIC beta agonists; ALLERGY treatment; ASPERGILLOSIS treatment; ASTHMA treatment; GASTROESOPHAGEAL reflux treatment; MENTAL illness treatment; THERAPEUTIC use of monoclonal antibodies; OBESITY treatment; DRUG therapy for asthma; MACROLIDE antibiotics; ANTIFUNGAL agents; SLEEP apnea syndrome treatment; ADRENOCORTICAL hormones; AEROSOL therapy; ASTHMA; DRUGS; PATIENT compliance; PATIENT education; SMOKING; SMOKING cessation; COMORBIDITY; SOCIAL support; TREATMENT effectiveness; DISEASE prevalence; SEVERITY of illness index; SYMPTOMS; THERAPEUTICS
- Publication
Clinical Medicine Insights: Circulatory, Respiratory & Pulmonary Medicine, 2011, Issue 5, p37
- ISSN
1179-5484
- Publication type
Article
- DOI
10.4137/CCRPM.S5535