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- Title
Targeting the Adaptive Molecular Landscape in Prostate Cancer: Dissection of the novel AKT/miR-145/ RAS Circuit.
- Authors
Serafin, Valentina; Zavatti, Manuela; Braglia, Luca; Bresolin, Silvia; Marmiroli, Sandra
- Abstract
The article presents a study on targeting the adaptive molecular landscape in prostate cancer. Topics include information on Aberrantly active PI3K/AKT signaling; results of clinical studies with such PI3K or AKT inhibitors; and rapid emergence of resistance triggered by interruption of negative feedback circuits or perturbation of pathway homeostasis.
- Subjects
PROSTATE cancer; NEUROSCIENCES; DISSECTION; RENIN-angiotensin system
- Publication
Italian Journal of Anatomy & Embryology / Archivio Italiano di Anatomia Ed Embriologia, 2022, Vol 126, p146
- ISSN
1122-6714
- Publication type
Article