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- Title
Validation of a Prediction Rule for the Diagnosis of Rheumatoid Arthritis in Patients with Recent Onset Undifferentiated Arthritis.
- Authors
Bedran, Zaida; Quiroz, Cristian; Rosa, Javier; Catoggio, Luis J.; Soriano, Enrique R.
- Abstract
Objectives. To validate van derHelm-vanMil score (vHvM) and new ACR/EULAR criteria for the diagnosis of rheumatoid arthritis (RA) in patients with undifferentiated arthritis (UA). Patients and Methods. Adult patients with UA (swelling ⩾2 joints of less than 6 months duration, without diagnosis, and never treated with disease modifying drugs). Results. Ninety-one patients were included. Mean age: 55.6 years (SD: 17.4), 74% females. Median symptoms duration was 2 months (IR: 1-4 months). Mean van der Helm-van Mil score was 6.9 (SD: 2). After a mean follow up of 6.2 months (SD: 6), 40.7% patients fulfilled ACR 1987 RA classification criteria, 28.6% fulfilled other diagnostic criteria, and 31% remained as UA. Receiver operator characteristic curve's (ROC's) area under the curve (AUC) for the vHvMscore for diagnosis of RA was 0.83. A cutoff value of 6.94 showed sensitivity of 81%and 79.7%specificity. For the new ACR/EULAR criteria, the ROC AUC was 0.93, and a value equal to or greater than 6 showed 86.5% sensitivity and 87% specificity. Conclusion. van der Helm-van Mil prediction score and the new ACR/EULAR criteria proved to be valuable for the diagnosis of RA in patients with early UA.
- Subjects
RHEUMATOID arthritis diagnosis; STANDARD deviations; ARTHRITIS patients; ARTHRITIS prevention; PHYSICAL therapy for arthritis
- Publication
International Journal of Rheumatology, 2013, p1
- ISSN
1687-9260
- Publication type
Article
- DOI
10.1155/2013/548502