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- Title
Ketorolac or fentanyl continuous infusion for post-operative analgesia in children undergoing ureteroneocystostomy.
- Authors
Jo, Y. Y.; Hong, J. Y.; Choi, E. K.; Kil, H. K.
- Abstract
Children undergoing ureteroneocystostomy suffer from post-operative pain due to the surgical incision and bladder spasm. A single-shot caudal block is a common technique for paediatric analgesia, but a disadvantage is the limitation of a short duration in spite of the additives co-administered. A few clinical trials have shown that ketorolac provides an effective post-operative analgesia and reduces the bladder spasms after ureteral implantation in children. We compared the efficacy of a continuous infusion of ketorolac and fentanyl in post-operative analgesia and bladder spasm in children who underwent ureteroneocystostomy. Fifty-two children were allocated to the ketorolac group (Group K, n=26) and fentanyl group (Group F, n=26). After general anaesthesia, a caudal block was performed with 1.5 ml/kg of 0.15% ropivacaine. At the beginning of surgery, an infusion was started after the bolus injection of ketorolac 0.5 mg/kg or fentanyl 1 μg/kg. An infusion device was programmed to deliver ketorolac 83.3 μg/kg/h or fentanyl 0.17 μg/kg/h for 48 h. Two of Group F and three of Group K were excluded from the study. Post-operative pain scores were similar between the two groups. One of Group K (4%) and seven of Group F (30.4%) experienced bladder spasms. The rescue analgesic requirements were significantly less in Group K. A Continuous infusion of ketorolac provided effective analgesia after operation in children who underwent ureteroneocystostomy as well as a low dosage of fentanyl. Ketorolac was more effective in reducing the frequency of bladder spasms and rescue analgesic requirements.
- Subjects
PEDIATRIC surgery; DISEASES; SURGICAL complications; PAIN in children; ANALGESIA; SURGICAL site; SPASMS; KETOROLAC; FENTANYL; THERAPEUTICS
- Publication
Acta Anaesthesiologica Scandinavica, 2011, Vol 55, Issue 1, p54
- ISSN
0001-5172
- Publication type
Article
- DOI
10.1111/j.1399-6576.2010.02354.x