We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Genetic Diversity of Human Metapneumovirus over 4 Consecutive Years in Australia.
- Authors
Mackay, Ian M.; Bialasiewicz, Seweryn; Jacob, Kevin C.; McQueen, Emily; Arden, Katherine E.; Nissen, Michael D.; Sloots, Theo P.
- Abstract
The molecular epidemiologic profile of human metapneumovirus (hMPV) infection has likely been skewed toward certain genetic subtypes because of assay-design issues, and no comprehensive studies have been conducted to date. Here, reverse-transcription polymerase chain reaction was used to screen 10,319 specimens from patients presenting to hospitals with suspected respiratory tract infections during 2001-2004. After analysis of 727 Australian hMPV strains, 640 were assigned to 1 of 4 previously described subtypes. hMPV was the most common pathogen detected, and subtype B1 was the most common lineage. Concurrent, annual circulation of all 4 hMPV subtypes in our study population was common, with a single, usually different hMPV subtype predominating in each year.
- Subjects
AUSTRALIA; RESPIRATORY infections; REVERSE transcriptase; POLYMERASE chain reaction; MOLECULAR epidemiology
- Publication
Journal of Infectious Diseases, 2006, Vol 193, Issue 12, p1630
- ISSN
0022-1899
- Publication type
Article
- DOI
10.1086/504260