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- Title
Peripheral arthritis in the course of inflammatory bowel diseases.
- Authors
Yüksel, İlhami; Ataseven, Hilmi; Başar, Ömer; Köklü, Seyfettin; Ertuğrul, İbrahim; Ülker, Aysel; Dağlı, Ülkü; Şaşmaz, Nurgül; Yüksel, Ilhami; Başar, Omer; Köklü, Seyfettin; Ertuğrul, Ibrahim; Ulker, Aysel; Dağlı, Ulkü; Saşmaz, Nurgül
- Abstract
<bold>Background: </bold>Musculoskeletal disorders are well-defined extra-intestinal manifestations of inflammatory bowel diseases (IBD). There is little data regarding the frequencies of IBD and extra-intestinal manifestations from Central and East Europe and Middle Eastern countries.<bold>Aims: </bold>To determine the prevalence of peripheral arthritis in IBD and to document the relationship to other extra-intestinal manifestations.<bold>Methods: </bold>Enrolled in the study were 357 patients who were diagnosed with IBD from December 2002 through January 2008. All of the patients underwent a detailed whole-body examination by a gastroenterologist and rheumatologist.<bold>Results: </bold>IBD-related peripheral arthritis (IBDPA) was found in 66 (18.5%) of the 357 patients (28.3% Crohn's disease, 13.5% ulcerative colitis; p=0.001 χ=11.62). IBDPA was more frequent in female patients (60.6 vs. 39.4%, p=0.000, χ=11.12). In eight (12.1%) cases, IBDPA occurred before the onset of IBD. Acute self-limiting episodes, recurrences of the attacks, and persistent symptoms of arthritis were present in 40 (60.6%), 26 (39.3%), and 29 (45.7%) patients, respectively. Arthritis was symmetrical in 33 (50%) cases. Knees (65.2%) and ankles (62.1%) were the most commonly affected joints. Erythema nodosum and pyoderma gangrenosum were more common among patients with IBDPA than patients without it (p=0.001, χ=10.49, and p=0.000 χ=25.77, respectively).<bold>Conclusions: </bold>IBDPA is a frequent extra-intestinal complication of IBD. Those of female gender and the presence of Crohn's disease, erythema nodosum and pyoderma gangrenosum have a higher risk to develop IBDPA.
- Subjects
EUROPE; MIDDLE East; INFLAMMATORY bowel diseases; MUSCULOSKELETAL system diseases; INTESTINAL diseases; CROHN'S disease; INFLAMMATION; GASTROENTEROLOGY; ULCERATIVE colitis; ARTHRITIS; ANKLE; KNEE; SEX distribution; DISEASE prevalence; RETROSPECTIVE studies; PYODERMA gangrenosum; ERYTHEMA nodosum; DISEASE complications
- Publication
Digestive Diseases & Sciences, 2011, Vol 56, Issue 1, p183
- ISSN
0163-2116
- Publication type
journal article
- DOI
10.1007/s10620-010-1260-z