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- Title
Cross-dressing proteins by olefin metathesis.
- Authors
Kirshenbaum, Kent; Arora, Paramjit S.
- Abstract
The article discusses the process of cross-dressing of proteins using olefin metathesis. It offers an overview of how modifications in protein structure can be made possible through metathesis catalysts and cites the study conducted by Benjamin G. Davis and his colleagues that describe the conversion of cysteine residue into dehydroalanine of protein surfaces. Also presented in the article are the different procedures related to protein conjugations.
- Subjects
CHEMICAL reactions; PROTEIN crosslinking; METATHESIS reactions; CROSSLINKING (Polymerization); ALKENES; BIOCHEMISTRY
- Publication
Nature Chemical Biology, 2008, Vol 4, Issue 9, p527
- ISSN
1552-4450
- Publication type
Article
- DOI
10.1038/nchembio0908-527