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- Title
Dietary Flavonoids: Mitigating Air Pollution's Cardiovascular Risks.
- Authors
Rocha-Velasco, Oscar Andrés; Morales-Suárez-Varela, María; Llopis-González, Agustín
- Abstract
Air pollution significantly impacts cardiovascular health, yet pollution reduction strategies in cardiovascular disease prevention remain limited. Dietary flavonoids show promise in protecting cardiovascular health, but their potential to mitigate air-pollution-induced risks is unexplored. This study investigates this research gap. Following PRISMA-ScR guidelines, literature from 2014–2024 was searched across MedLine/PubMed, ScienceDirect, and MDPI databases. Of 463 identified studies, 53 were eligible for analysis based on PICO criteria. Findings revealed significant impacts of air pollution on cardiovascular health, including increased disease risks and mortality. Flavonoid intake demonstrated protective effects against these risks. Flavonoid mechanisms include improved endothelial function, antioxidant and anti-inflammatory effects, blood pressure regulation, antiplatelet effects, cardioprotection, and enhanced lipid and glucose metabolism. Higher flavonoid intake was consistently associated with reduced cardiovascular risks. While reducing pollution remains crucial, promoting flavonoid-rich diets is a promising complementary strategy. Public health initiatives should raise awareness about these benefits. Further research on direct interactions between flavonoid intake and air pollution exposure is needed. Current evidence supports integrating dietary interventions into broader strategies to reduce air pollution's cardiovascular impacts.
- Subjects
AIR pollution prevention; ENDOTHELIUM physiology; INFLAMMATION prevention; LIPID metabolism; GLUCOSE metabolism; CARDIOVASCULAR disease related mortality; AIR pollution; ANTI-inflammatory agents; CARDIOVASCULAR diseases; FOOD consumption; FLAVONOIDS; CARDIOVASCULAR diseases risk factors; SYSTEMATIC reviews; MEDLINE; ENDOTHELIAL cells; ANTIOXIDANTS; ONLINE information services; PLATELET aggregation inhibitors; PUBLIC health; HEALTH promotion; DIETARY supplements; DIET
- Publication
Nutrients, 2024, Vol 16, Issue 16, p2647
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu16162647