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- Title
Lipids and Women's Health: Recent Updates and Implications for Practice.
- Authors
Fay, Kathryn E.; Farina, Lauren A.; Burks, Heather R.; Wild, Robert A.; Stone, Neil J.
- Abstract
The obstetrician/gynecologist frequently serves as the primary care physician for women. Specialty-specific guidelines vary in screening recommendations for lipid disorders; women's health practitioners often follow recommendations to screen at age 45 in the absence of other risk factors. However, 2013 American College of Cardiology/American Heart Association cholesterol guidelines recommend screening at age 21 to capture those at risk of cardiovascular disease and allow for early intervention with lifestyle and, in the most severe cases, evidence-based statins. We discuss the care of women who primarily benefit from screening: those with familial hypercholesterolemia (FH), those with the metabolic syndrome (MetS) or polycystic ovary syndrome, and those with hypertriglyceridemia. Those with FH have elevated low-density lipoprotein cholesterol from birth and a propensity for premature coronary heart disease. Early recognition of FH can allow risk-reducing interventions, as well as identification of additional affected relatives. Early detection of metabolic variables, such as in the MetS and hypertriglyceridemia, can lead to an enhanced focus on physical activity and heart-healthy diet. Finally, we discuss a practical approach to lipid management and review concerns regarding drug safety. Our objective is to provide a current overview of cardiovascular risk factor optimization that women's health practitioners can use in identifying and/or treating patients at risk for cardiovascular disease and diabetes.
- Subjects
CORONARY heart disease risk factors; DIABETES risk factors; METABOLIC syndrome diagnosis; CARDIOVASCULAR diseases risk factors; DIET; HYPERLIPIDEMIA; LOW density lipoproteins; MEDICAL protocols; MEDICAL screening; POLYCYSTIC ovary syndrome; WOMEN'S health; PHYSICAL activity; EARLY diagnosis; FAMILIAL hypercholesterolemia
- Publication
Journal of Women's Health (15409996), 2019, Vol 28, Issue 6, p752
- ISSN
1540-9996
- Publication type
Article
- DOI
10.1089/jwh.2017.6745