We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Topographical Control of Preosteoblast Culture by Shape Memory Foams.
- Authors
Xie, Ruiqi; Hu, Jinlian; Guo, Xia; Ng, Frankie; Qin, Tingwu
- Abstract
Here, the authors present a thermo-responsive shape memory polymer (SMP) foam that can be programmed to control the preosteoblast behavior by changing porous architecture during cell cultivation. The preosteoblast cells are seeded on the SMP foams with temporarily compressed pore structure. Results show that cells preferentially align along the pore length direction. After the pore recovery at 37 °C, cells remain attached and viable but change their topography in a tangential direction along the pore edge. This work indicates the shape-memory actuated porous structure in SMP foam can control the cell behavior. This may provide an effective method for studying cell responses to dynamic environment and facilitate the healthy and optimal development of tissue engineering.
- Subjects
SHAPE memory polymers; SURFACE topography; TISSUE engineering
- Publication
Advanced Engineering Materials, 2017, Vol 19, Issue 1, pn/a
- ISSN
1438-1656
- Publication type
Article
- DOI
10.1002/adem.201600343