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- Title
Clinical applications of alanine/electron spin resonance dosimetry.
- Authors
Baffa, Oswaldo; Kinoshita, Angela
- Abstract
This paper discusses the clinical applications of electron spin resonance (ESR) dosimetry focusing on the ESR/alanine system. A review of few past studies in this area is presented offering a critical overview of the challenges and opportunities for extending this system into clinical applications. Alanine/ESR dosimetry fulfills many of the required properties for several clinical applications such as water-equivalent composition, independence of the sensitivity for the energy range used in therapy and high precision. Improvements in sensitivity and the development of minidosimeters coupled with the use of a spectrometer of higher microwave frequency expanded the possibilities for clinical applications to the new modalities of radiotherapy (intensity-modulated radiation therapy and radiosurgery) and to the detection of low doses such as those present in some radiological image procedures.
- Subjects
ALANINE; ELECTRON spin polarization; RADIATION dosimetry; THERAPEUTICS; MEDICAL electronics; ELECTRON paramagnetic resonance
- Publication
Radiation & Environmental Biophysics, 2014, Vol 53, Issue 2, p233
- ISSN
0301-634X
- Publication type
Article
- DOI
10.1007/s00411-013-0509-2