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- Title
Gastro-esophageal reflux and cow's milk intolerance in infants and children: a prospective clinical, physiological, and histological study.
- Authors
Ida, Shinobu; Kubota, Mitsuru; Yoshimura, Norikazu; Hirayama, Satoru; Mushiake, Sotaro; Kuroda, Seika; Okuyama, Hiroomi; Ooue, Takaharu; Kubota, Akio; Kawahara, Hisayoshi
- Abstract
Aim : To show the clinical, physiological and histological characteristics in GER with cow's milk intolerance Methods : Nine children with GERD tess than 6 years old who had at least recurrent vomiting as ther symptom were studied. Endoscopic and histologic diagnosis, gastric scintigraphy and 24 h-pH monitoring, blood tests were done. Results : All children had cow's milk intolerance clinically. Acid reflux in esophagus and delayed gastric emptying were shown. Duodenitis with histamine and substance P and mild esophagitis were present in these children. Conclusions : Duodenitis with chemical mediators secondary to cow's milk intolerance may play an important role for the cause of GER in children.
- Subjects
GASTROESOPHAGEAL reflux in children; LACTOSE intolerance in children; MILK; DUODENAL diseases; HISTAMINE
- Publication
Asia Pacific Journal of Clinical Nutrition, 2002, Vol 11, pS50
- ISSN
0964-7058
- Publication type
Article