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- Title
Malignant syphilis in an AIDS patient.
- Authors
Santos, T.; Castro, I.; Dahia, M.; Azevedo, M.; Silva, G.; Motta, R.; Cunha Pinto, J.; Almeida Ferry, F.
- Abstract
Malignant syphilis is an uncommon, but not unknown, ulcerative variation of secondary syphilis. The lesions typically begin as papules, which quickly evolve to pustules and then to ulcers with elevated edges and central necrosis. It is usually, but not mandatory, found in patients with some level of immunosuppression, such as HIV patients, when the TCD4 cell count is >200 cells/mm. Despite the anxiety the lesions cause, this form of the disease has a good prognosis. The general symptoms disappear right after the beginning of treatment, and lesions disappear over a variable period. This study reports the case of a 27-year-old man who has been HIV positive for 6 years, uses antiretroviral therapy incorrectly, has a TCD4 cell count of 340 cells/mm, a VDRL of 1:128 and itchy disseminated hyperchromic maculopapular lesions with rupioid crusts compatible with malignant syphilis.
- Subjects
DIFFERENTIAL diagnosis; HIV-positive persons; SKIN diseases; SYPHILIS; SYMPTOMS
- Publication
Infection, 2015, Vol 43, Issue 2, p231
- ISSN
0300-8126
- Publication type
Report
- DOI
10.1007/s15010-014-0698-x