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- Title
The Roles of Circular RNAs in Ischemic Stroke through Modulating Neuroinflammation.
- Authors
Xin Gu; Lingfei Li; Biao Chen; Yuyao Zhang; Yongji Zhou; Keqin Liu; Wenqin Xia; Xiaoqin Li; Zheng Zhang; Huanqing Shi; Jinyu Huang; Beibei Gao; Lin Jiang; Anwen Shao; Congguo Yin
- Abstract
Ischemic stroke (IS) remains a serious threat to human health. Neuroinflammatory response is an important pathophysiological process after IS. Circular RNAs (circRNAs), a member of the non-coding RNA family, are highly expressed in the central nervous system and widely involved in regulating physiological and pathophysiological processes. This study reviews the current evidence on neuroinflammatory responses, the role of circRNAs in IS and their potential mechanisms in regulating inflammatory cells, and inflammatory factors affecting IS damage. This review lays a foundation for future clinical application of circRNAs as novel biomarkers and therapeutic targets.
- Subjects
ISCHEMIC stroke; CIRCULAR RNA; NEUROINFLAMMATION; CENTRAL nervous system; NON-coding RNA
- Publication
Journal of Integrative Neuroscience, 2024, Vol 23, Issue 4, p1
- ISSN
0219-6352
- Publication type
Article
- DOI
10.31083/j.jin2304087