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- Title
TGF‐β1 down‐regulates inflammatory cytokine‐induced VCAM‐1 expression in cultured human glomerular endothelial cells.
- Authors
Park, Su‐Kil; Yang, Won Seok; Lee, Sang Koo; Ahn, Hanjong; Park, Jung Sik; Hwang, Onyou; Lee, Jae Dam
- Abstract
Background. Endothelial cells are active participants in the processes controlling coagulation, inflammation and the immune response. Variations are recognized between endothelia isolated from different vascular beds as well as from different species. Though transforming growth factor‐β1 (TGF‐β1) has been known to have an anti‐inflammatory action, little is known about its effect on expression of cellular adhesion molecules during the inflammatory process in human glomerular endothelial cells. The aim of this study was to determine the effect of TGF‐β1 on the inflammatory cytokine‐induced expression of vascular cell adhesion molecule‐1 (VCAM‐1) in cultured human glomerular endothelial cells.
- Publication
Nephrology Dialysis Transplantation, 2000, Vol 15, Issue 5, p596
- ISSN
0931-0509
- Publication type
Article
- DOI
10.1093/ndt/15.5.596