We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Low-level laser therapy improves repair following complete resection of the sciatic nerve in rats.
- Authors
Medalha, Carla; Gangi, Giuliana; Barbosa, Caroline; Fernandes, Marcela; Aguiar, Odair; Faloppa, Flávio; Leite, Vilnei; Renno, Ana
- Abstract
The aim of this study is to analyze the effects of low-level laser therapy (LLLT) on the regeneration of the sciatic nerve in rats following a complete nerve resection. Male Wistar rats were divided into a control injury group, injury groups irradiated with a 660-nm laser at 10 or 50 J/cm, and injury groups irradiated with an 808-nm laser at 10 or 50 J/cm. Treatment began 24 h following nerve resection and continued for 15 days. Using the sciatic functional index (SFI), we show that the injured animals treated with 660 nm at 10 and 50 J/cm had better SFI values compared with the control injury and the 808-nm groups. Animals irradiated with the 808-nm laser at 50 J/cm show higher values for fiber density than do control animals. In addition, axon and fiber diameters were larger in animals irradiated with 660 nm at 50 J/cm compared to the control group. These findings indicate that 660-nm LLLT is able to provide functional gait recovery and leads to increases in fiber diameter following sciatic nerve resection.
- Subjects
MEDICAL lasers; SCIATIC nerve surgery; NERVOUS system regeneration; LOW-level radiation; LABORATORY rats; GAIT disorders; SURGICAL excision
- Publication
Lasers in Medical Science, 2012, Vol 27, Issue 3, p629
- ISSN
0268-8921
- Publication type
Article
- DOI
10.1007/s10103-011-1008-9