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- Title
Tobacco Mosaic Virus as a Carrier for Small Molecules. II. Cooperative affinity labeling of membrane vesicles with a TMV angiotensin conjugate. Preliminary communication.
- Authors
Kriwaczek, Verena M.; Bonnafous, Jean-Claude; Müller, Martin; Schwyzer, Robert
- Abstract
A (3-mercapto-1-succinyl)-TMV ϵ-maleimidohexanoyl-[1-asparagine, 5-valine]-angiotensin II conjugate was prepared and used for cooperative affinity labeling of bovine adrenal cortex cell membrane vesicles containing angiotensin-binding sites. The labeling was demonstrated by electron microscopy and by CsCl and sucrose density gradient centrifugation Preliminary evidence for specific binding and for the postulated cooperative affinity interaction is produced.
- Publication
Helvetica Chimica Acta, 1978, Vol 61, Issue 4, p1241
- ISSN
0018-019X
- Publication type
Article
- DOI
10.1002/hlca.19780610406