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- Title
Epidemiology of infertility in China: a population-based study.
- Authors
Zhou, Z.; Zheng, D.; Wu, H.; Li, R.; Xu, S.; Kang, Y.; Cao, Y.; Chen, X.; Zhu, Y.; Chen, Z‐J; Mol, B. W.; Qiao, J.; Chen, Z-J
- Abstract
<bold>Objective: </bold>To assess the current prevalence of and risk factors for infertility among couples of reproductive age in China.<bold>Design: </bold>Population-based cross-sectional study.<bold>Setting: </bold>We approached 25 270 couples in eight provinces/municipalities, of whom 18 571 (response rate 74%) were interviewed.<bold>Population: </bold>Couples living together and married for more than 1 year, of whom the female spouse was 20-49 years old.<bold>Methods: </bold>Women were approached via telephone and face-to-face conversation to complete the standardised and structured questionnaire by trained interviewers.<bold>Main Outcome Measures: </bold>Prevalence of and risk factors for infertility.<bold>Results: </bold>Among women 'at risk' of pregnancy, the prevalence of infertility was 15.5% (2680/17 275). Among 10 742 women attempting to become pregnant, the prevalence of infertility was 25.0% (2680/10 742), which increased with age in the second population. Among women who failed to achieve pregnancy in the last 12 months, 3470 finished our questionnaire about fertility care, and 55.2% (1915/3470) of them had sought medical help. Sociodemographic risk factors for infertility included lower educational level [adjusted odds ratio (aOR) 3.4, 95% CI 2.0-5.5] and employment (aOR 2.3, 95% CI 1.9-2.9). Clinical risk factors were irregular menstrual cycle (aOR 1.8, 95% CI 1.2-2.5), light menstrual blood volume (aOR 1.6, 95% CI 1.2-2.0), history of cervicitis (aOR 1.5, 95% CI 1.2-2.0) and endometriosis (aOR 3.1, 95% CI 1.1-9.3), previous stillbirth (aOR 2.1, 95% CI 1.3-3.3) and miscarriage (aOR 2.7, 95% CI 2.1-3.5). In addition, history of operation was a significant risk factor of infertility.<bold>Conclusions: </bold>Among couples of reproductive age in China, the prevalence of infertility was 25%, and almost half of the couples experiencing infertility had not sought medical help.<bold>Tweetable Abstract: </bold>In China, 25% of couples actively attempting to become pregnant suffered infertility.
- Subjects
CHINA; MENTAL health; DEMOGRAPHY; FEMALE reproductive organ diseases; INFERTILITY; QUALITATIVE research; SOCIOECONOMIC factors; DISEASE prevalence; FAMILY planning
- Publication
BJOG: An International Journal of Obstetrics & Gynaecology, 2018, Vol 125, Issue 4, p432
- ISSN
1470-0328
- Publication type
journal article
- DOI
10.1111/1471-0528.14966