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- Title
Epididymal approaches to male contraception.
- Authors
Drevet, Joël R.
- Abstract
Today, a vast arsenal of contraceptive methods interfering at different levels of the female reproductive axis is available. This is not the case for men for whom, until now, there is no reliable male reversible method and for whom vasectomy, condom and withdrawal are the only options available. Despite this limited supply, more than one third of all contraceptive methods used worldwide rely on the cooperation of the male partner. Besides developing hormonal approaches to stop sperm production, there may be attractive approaches that will interfere with sperm functions rather than production. Sperm functions are primarily established during post-testicular maturation, with the epididymis accounting for the majority. The purpose of this review is to present some of the promising and/or already abandoned leads that emerge from research efforts targeting the epididymis and its activities as potential means to achieve male post-meiotic contraception.
- Publication
Basic & Clinical Andrology, 2018, Vol 28, Issue 1, pN.PAG
- ISSN
2051-4190
- Publication type
Article
- DOI
10.1186/s12610-018-0078-y