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- Title
Sodium‐glucose co‐transporter‐2 inhibitors and protection from cardiovascular death: Is it all about heart failure?
- Authors
Caruso, Irene; Cignarelli, Angelo; Laviola, Luigi; Giorgino, Francesco
- Abstract
Interestingly, treatment with SGLT-2is significantly reduced overall CV death and CV death attributable to worsening of HF or cardiogenic shock (RR 0.70, 95% CI 0.52-0.94, I P i = .02) with moderate heterogeneity in the meta-analysis (I SP 2 sp = 65%) (Figure 1A,B). Sodium-glucose co-transporter-2 inhibitors and protection from cardiovascular death: Is it all about heart failure? Nevertheless, the highest proportion of CV death as a result of HF or cardiogenic shock occurred in EMPA-REG Outcome, while the lowest was in VERTIS-CV.
- Subjects
SUDDEN death; HEART failure; NEPRILYSIN; CARDIOVASCULAR disease related mortality; SODIUM-glucose cotransporter 2 inhibitors
- Publication
Diabetes, Obesity & Metabolism, 2021, Vol 23, Issue 9, p2194
- ISSN
1462-8902
- Publication type
Article
- DOI
10.1111/dom.14444