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- Title
COMPARATIVE STUDY OF INTRA LESIONAL TRIAMCINOLONE ACETONIDE + 5-FLUOROURACIL VERSUS TRIAMCINOLONE ACETONIDE + VERAPAMIL IN THE TREATMENT OF KELOIDS.
- Authors
Kumar, P. S. Raja Ravi; Mouli, M. Vijaya Chandra; Priyanka, D. Sindhu; Bai, M. Manjula; E. R., Kishan Reddy; Greeshma, Tathapudi
- Abstract
Background: Keloids are common problem with significant recurrence. Despite of many options available, there is no standard acceptable treatment for keloid. This study compares the combinations of triamcinolone acetonide + 5-Fluorouracil versus triamcinolone acetonide + verapamil in the treatment of keloids. Materials and Methods: This is a randomized study for a period of one year. 60 patients were randomly allocated into two groups. Group 1 - TAC + Verapamil, Group 2 - TAC + 5-FU. Intralesional injection was given every 3 weeks till 24 weeks. Results: There was reduction of scar height, vascularity, pigmentation and pliability. Improvement in terms of height, vascularity, pliability was faster with TAC+5FU compared to TAC + Verapamil. Conclusion: TAC+5FU combination were effective in keloids in comparison to TAC +Verapamil. The combination offered the balanced benefits of faster and more effective response.
- Subjects
TRIAMCINOLONE acetonide; KELOIDS; VERAPAMIL; FLUOROURACIL; COMPARATIVE studies
- Publication
International Journal of Medicine & Public Health, 2023, Vol 13, Issue 4, p34
- ISSN
2230-8598
- Publication type
Article
- DOI
10.5530/ijmedph.2023.4.7