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- Title
Formulation and stability enhancement using vitamin A encapsulation in ocular abnormalities: A scientific review.
- Authors
Chandan, C.; Pardhe, H. A.; Nagappan, K.; Phani Kumar, G.; Sushma, B. V.; Jeyaprakash, M. R.
- Abstract
The relationship between vitamin A, retinol activity, and eye health has been briefly elucidated. Based on certain reports, vitamin A and retinol activity can help overcome vitamin A insufficiency i.e., xerophthalmia. The present review assesses vitamin A sources, ß-carotene and ß-cryptoxanthin in vitamin A metabolism, retinol and xerophthalmia, and new application of vitamin A in mitigating xerophthalmia. Vitamin A and its precursors are sensitive, and could lose their biological activity when exposed to light or oxygen. In this context, encapsulation may act as a protection strategy for enhancing vitamin A's biological functions under adverse conditions. With the belief that vitamin A and retinol activity have a long-term association with xerophthalmia, the present review discusses the relationship between vitamin A consumption and its precursors, as well as the physiological effects of vitamin A on xerophthalmia. In conclusion, further research using free and encapsulated forms of vitamin A to prevent vitamin A deficiency and manage xerophthalmia should be emphasised.
- Subjects
VITAMIN A; VITAMINS; VITAMIN deficiency; HUMAN abnormalities; METABOLISM
- Publication
International Food Research Journal, 2023, Vol 30, Issue 3, p564
- ISSN
1985-4668
- Publication type
Article
- DOI
10.47836/ifrj.30.3.02