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- Title
Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
- Authors
Fernandes, Matheus Santos de Sousa; Fidelis, Débora Eduarda da Silvia; Aidar, Felipe J.; Badicu, Georgian; Greco, Gianpiero; Cataldi, Stefania; Santos, Gabriela Carvalho Jurema; de Souza, Raphael Frabrício; Ardigò, Luca Paolo
- Abstract
Background: To summarize available evidence in the literature on the impacts of CoQ10 supplementation on metabolic, biochemical, and performance outcomes in athletes. Methods: Six databases, Cochrane Library (33 articles), PubMed (90 articles), Scopus (55 articles), Embase (60 articles), SPORTDiscus (1056 articles), and Science Direct (165 articles), were researched. After applying the eligibility criteria, articles were selected for peer review independently as they were identified by June 2022. The protocol for this systematic review was registered on PROSPERO (CRD42022357750). Results: Of the 1409 articles found, 16 were selected for this systematic review. After CoQ10 supplementation, a decrease in oxidative stress markers was observed, followed by higher antioxidant activity. On the other hand, lower levels of liver damage markers (ALT); Aspartate aminotransferase (AST); and Gamma-glutamyl transpeptidase (γGT) were identified. Finally, we found a reduction in fatigue indicators such as Creatine Kinase (CK) and an increase in anaerobic performance. Conclusions: This systematic review concludes that supplementation with orally administered CoQ10 (30–300 mg) was able to potentiate plasma antioxidant activity and anaerobic performance, reducing markers linked to oxidative stress and liver damage in athletes from different modalities aged 17 years old and older.
- Subjects
MEDICAL databases; ONLINE information services; GAMMA-glutamyltransferase; MEDICAL information storage &; retrieval systems; SYSTEMATIC reviews; ATHLETES; SPORTS; CREATINE kinase; UBIQUINONES; DIETARY supplements; OXIDATIVE stress; ATHLETIC ability; MEDLINE; INFORMATION storage &; retrieval systems; ASPARTATE aminotransferase; ALANINE aminotransferase; ANAEROBIC threshold
- Publication
Nutrients, 2023, Vol 15, Issue 18, p3990
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu15183990