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- Title
Combined Screening With Ultrasound and Mammography vs Mammography Alone in Women at Elevated Risk of Breast Cancer.
- Authors
Berg, Wendie A.; Blume, Jeffrey D.; Cormack, Jean B.; Mendelson, Ellen B.; Lehrer, Daniel; Böhm-Vélez, Marcela; Pisano, Etta D.; Jong, Roberta A.; Evans, W. Phil; Morton, Mariyln J.; Mahoney, Mary C.; Larsen, Linda Hovanessian; Barr, Richard G.; Farria, Dione M.; Marques, Helga S.; Boparai, Karen
- Abstract
The article presents a study comparing the diagnostic efficacy of screening with ultrasound plus mammography versus mammography alone in women with an increased risk of developing breast cancer. The design, setting and participants of the study which involved 2,809 women are detailed. The outcomes of both screening methods were measured for diagnostic yield, sensitivity, specificity, and diagnostic accuracy. Researchers concluded that adding ultrasound screening to mammography will significantly increase the number of breast cancers diagnosed among high-risk women, but it will also raise the number of false positives.
- Subjects
BREAST cancer magnetic resonance imaging; MAMMOGRAMS; MEDICAL screening evaluation; ULTRASOUND contrast media; DISEASES in women; CANCER diagnosis
- Publication
JAMA: Journal of the American Medical Association, 2008, Vol 299, Issue 18, p2151
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.299.18.2151