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- Title
Rearrangement in the Breakpoint Cluster Region and the Clinical Philadelphia-Negative Chronic Myelogenous Leukemia.
- Authors
Kurzrock, Razelle; Blick, Mark B.; Talpaz, Moshe; Velasquez, William S.; Trujillo, Jose M.; Kouttab, Nicola M.; Kloetzer, William S.; Arlinghaus, Ralph B.; Gutterman, Jordan U.
- Abstract
Argues that breakpoint cluster region rearrangement in Philadelphia (Ph)-negative chronic myelogenous leukemia can result in expression of the aberrant fusion protein. Information on the preparation of DNA and blot hybridization; Characteristics of patients with Ph-negative chronic myelogenous leukemia; Importance of the presence of the Ph chromosome.
- Subjects
MYELOID leukemia; NUCLEIC acid hybridization; CHROMOSOMES
- Publication
Annals of Internal Medicine, 1986, Vol 105, Issue 5, p673
- ISSN
0003-4819
- Publication type
Article
- DOI
10.7326/0003-4819-105-5-673