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- Title
Exploration of Inflammatory Biomarkers and Psychological Cardiovascular Disease Risk Factors Among Community Dwelling Adults: A Gender Comparison Study.
- Authors
Hung, Hsuan-Man; Chen, Ming-Fu; Lee, Huan-Fang; Wang, Hui-Ling
- Abstract
Patients with rheumatic disease (RD) are at high risk for cardiovascular disease (CVD), which is the leading non-communicable chronic disease cause of death worldwide. Inflammatory biomarkers and psychological health status are reliable predictors of CVD in patients with RD. The primary aim of this study was to compare the inflammatory biomarkers and psychological CVD risk factors (CRFs) between a group of community-dwelling adults with RD and CRFs and a group of their peers with CRFs only. The secondary aim of this study was to analyze and compare the collected data by gender in the RD group. Data were collected and analyzed from 355 participants, with the 135 participants with physician-diagnosed RD assigned to the RD group and the remainder (n = 220) assigned to the comparison group. The measures used included a demographic datasheet, medical information, serum homocysteine (Hcy) levels, high sensitive C-reactive protein (hs-CRP) levels, and depression and global sleep-quality scale scores. The RD group had higher ratios of hypertension and depression diagnoses than the comparison group. The gender analysis of the RD group found significantly more-severe sleep disturbances in women than men and a significantly higher mean value of Hcy in men than women. The women in the RD group were significantly older, less educated, and less employed than their male counterparts and thus may be presumed to at higher risk of health illiteracy. Gender-tailored interventions to modify the risk factors of CVD identified in this study for patients with RD are recommended.
- Subjects
CARDIOVASCULAR diseases risk factors; BIOMARKERS; C-reactive protein; SLEEP quality; HYPERTENSION; HOMOCYSTEINE; MINORITIES; INFLAMMATION; HEALTH status indicators; FISHER exact test; RISK assessment; COMPARATIVE studies; HEALTH literacy; CRONBACH'S alpha; T-test (Statistics); INDEPENDENT living; DESCRIPTIVE statistics; MENTAL depression; CHI-squared test; ANALYSIS of covariance; RESEARCH funding; RHEUMATISM; DEMOGRAPHY; DATA analysis software; PSYCHOLOGICAL stress; DISEASE risk factors; ADULTS
- Publication
Biological Research for Nursing, 2024, Vol 26, Issue 1, p139
- ISSN
1099-8004
- Publication type
Article
- DOI
10.1177/10998004231197845